Which of the following is NOT a hypercoagulable state? Select all that apply.

Hemophilia A is characterized by a deficiency in clotting factor VIII, leading to impaired coagulation and an increased risk of bleeding rather than clotting. This condition results in a hypocoagulable state, meaning the blood does not clot effectively. Individuals with hemophilia A are more prone to bleeding episodes as their ability to form blood clots is compromised.

In contrast, the other conditions listed involve mechanisms that enhance the propensity for clot formation. Factor V Leiden mutation increases the risk of thrombosis due to a mutation that makes factor V resistant to inactivation by activated protein C, leading to a hypercoagulable state. Pregnancy also heightens the risk of clotting due to increased levels of procoagulant factors and changes in blood flow dynamics, which together create an environment more conducive to clot formation.

Thus, hemophilia A stands out as the condition that does not contribute to a hypercoagulable state, making it the correct answer in identifying conditions that are not associated with increased clotting tendencies.