Which clinical measurement is NOT commonly seen with Cushing syndrome?

In the context of Cushing syndrome, hyponatremia is not a typical clinical measurement associated with the condition. Cushing syndrome is characterized by an excess of cortisol production, often leading to various metabolic and physiological alterations.

One of the hallmark features of Cushing syndrome is the presence of hypertension, which arises from cortisol's effects on blood pressure regulation, including increased vascular reactivity and sodium retention. Elevated cortisol levels are a defining characteristic of the syndrome itself, as the condition is typically caused by excess production from the adrenal glands, often due to a tumor or adrenal hyperplasia.

Hypokalemia is also often present due to the renal effects of cortisol. High levels of cortisol can increase the excretion of potassium, leading to lower serum potassium levels.

In contrast, hyponatremia, which refers to low sodium levels in the blood, is not commonly associated with Cushing syndrome. In fact, patients may present with normal or even elevated sodium levels as a result of cortisol-induced sodium retention. Therefore, hyponatremia does not fit the typical profile of clinical measurements seen with Cushing syndrome, making it the correct answer.