What type of necrosis is commonly associated with tuberculosis?

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Caseous necrosis is specifically associated with tuberculosis due to the characteristic appearance of the necrotic tissue that results from the infection. In tuberculosis, the immune response leads to the formation of granulomas, which are collections of macrophages that attempt to wall off the bacteria causing the infection. Within these granulomas, the central area often undergoes caseous necrosis, giving it a cheese-like (caseous) consistency. This type of necrosis reflects a combination of coagulative and liquefactive necrosis but is distinctly recognized by the necrotic tissue's unique appearance and is pathognomonic for tuberculosis and certain other chronic granulomatous infections.

Other types of necrosis, such as coagulative and liquefactive necrosis, have different characteristics and underlying causes. Coagulative necrosis typically occurs due to ischemia or infarction in tissues, while liquefactive necrosis involves the transformation of tissue into a liquid viscous mass, often seen in brain injury or certain bacterial infections. Apoptosis, on the other hand, is a programmed cell death process that does not involve the inflammation that typically accompanies necrosis. Therefore, caseous necrosis is the most appropriate and distinctive association with tuberculosis, highlighting the unique pathological changes that occur

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