What is a possible cause of tissue atrophy?

Tissue atrophy refers to the decrease in the size or number of cells in a tissue, leading to a reduction in tissue mass. Nutritional deprivation is a key factor that can lead to this condition. When tissues do not receive adequate nutrients, the cells can begin to break down and shrink due to insufficient energy and building blocks for maintenance and growth. This lack of essential nutrients impacts cellular function and can result in a catabolic state where tissue is broken down for energy.

In contrast, increased physical activity typically stimulates muscle growth and can lead to hypertrophy rather than atrophy. Excessive hormonal stimulation usually promotes cell growth and function, which can enhance tissue size. Increased blood flow generally supports tissue health by delivering essential nutrients and oxygen, further helping to prevent atrophy. Thus, nutritional deprivation stands out as a direct and significant cause of tissue atrophy.