For a patient in stage 4 kidney disease, which GFR value would typically be expected?

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In stage 4 kidney disease, the glomerular filtration rate (GFR) typically declines significantly, indicating severe loss of kidney function. A GFR value around 15 to 29 mL/min/1.73m² is generally associated with stage 4 chronic kidney disease. Therefore, an indicated GFR of 25 mL/min/1.73m² fits within this range and reflects the substantial compromise in renal function that characterizes this stage of kidney disease.

The values representing GFR at higher ranges, such as 42 mL/min/1.73m² and 70 mL/min/1.73m², are more characteristic of earlier stages of kidney disease—stage 3 or stage 2, for instance. A GFR of 14 mL/min/1.73m², while close, indicates stage 5 kidney disease or end-stage renal disease, where kidney replacement therapy is often required. Thus, the answer of 25 mL/min/1.73m² is most suitable as it aligns clearly with the expected GFR for a patient in stage 4 kidney disease.

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